Acute heart failure in various pathological conditions. The syndrome of “low cardiac output” in patients after winstrol for sale cardiac surgery, acute hypotension. Poisoning (to enhance diuresis).Hypersensitivity to the drug’s components (including other sympathomimetics), idiopathic winstrol for sale hypertrophic subaortic stenosis, hyperthyroidism, pheochromocytoma, angle-closure glaucoma, benign winstrol for sale prostatic hyperplasia with clinical manifestations, tachyarrhythmia, ventricular fibrillation of the heart, under the age of 18 years.
Be wary. Hypovolemia, marked aortic stenosis, myocardial infarction, cardiac arrhythmias (ventricular fibrillation, atrial fibrillation), metabolic acidosis, hypercapnia, hypoxia, hypertension in the “small” circle of blood circulation, occlusive vascular disease in history (arterial thrombosis, atherosclerosis obliterans trombanginit, frostbite, occlusive disease, Raynaud’s disease), pregnancy, lactation; asthma (if you have a history of hypersensitivity to disulfite), diabetes mellitus.
Dosage and administration
Intravenously, the dose is determined individually.
The usual starting dose of 5.2 mcg / kg / min, depending on the result of the dose can be increased to 5 – 10 mcg / kg / min. Doses of 20 ug / kg / min are rarely used, but in severe cases the dose may be increased to 50 mg / kg / min.
Rule of a solution: dilution of the concentrate for solution for infusion 40 mg / ml using 0.9% sodium chloride solution, 5% dextrose solution. The resulting solution contains about 80 micrograms of in 1 ml (corresponding to 96 mg of hydrochloride). 1 ml of the resulting solution = 20 drops.
The resulting (reduced) the solution should be used within 12 hours.
On the part of the cardiovascular system: tachycardia or bradycardia, chest pain, increased or decreased blood pressure, conduction disorders, expanding the QRS complex, vasospasm, winstrol for sale when used in high doses – arrhythmia.
From the digestive system: nausea, vomiting, bleeding from the gastrointestinal tract.
From the nervous system: headache, anxiety, tremor.
Allergic reactions: in patients with bronchial asthma – bronchospasm, impairment of consciousness, shock.
Other: shortness of breath, azotemia, piloerection, rarely – polyuria.
Local reactions: in contact with the drug under the skin – skin necrosis, subcutaneous tissue.
Overdose Symptoms: . Excessive increase in blood pressure, spasms of peripheral arteries, tachycardia, ventricular arrythmia, angina, dyspnea, headache, agitation treatment: due to the rapid clearance of from the body these phenomena cropped dose reduction or cessation of administration, the ineffectiveness – alpha-blockers short-acting.
Interaction with other drugs
Pharmaceutical incompatible with alkaline solutions, oxidizing agents, iron salts, thiamine (vitamin contributes to the destruction).
Sympathomimetic effect reinforce adrenostimulyatorov, MAO inhibitors (increase duration and increased cardio and pressor effects), guanethidine; diuretic – diuretic; cardiotoxic – reinforce medicaments for inhalation general anesthesia, hydrocarbon derivatives cyclopropane (increased risk of serious atrial or ventricular arrhythmias), tricyclic antidepressants maprolitin (risk of cardiac arrhythmias, hypertension or severe hyperpyrexia), cocaine; butyrophenones impaired and beta-blockers (propranolol).
Akaloidy ergot and derivatives (ergometrine, ergotamine, metilergometrin) and oxytocin increases the vasoconstrictor effect of and the risk of ischemia and gangrene and severe hypertension, up to intracranial hemorrhage.
weaken hypotensive effect guanadrel, guanethidine, mecamylamine, methyldopa, Rauwolfia alkaloids (last prolong the effect of ).
snizhet nitrate antianginal effect, which in turn can reduce the pressor effect sympathomimetic and increase the risk of hypotension (simultaneous application is permitted depending on achieving the desired therapeutic effect).
In an application with levodopa increases the likelihood of arrhythmias; with thyroid hormones – may increase as the action of , and thyroid hormones.
Phenytoin may contribute to the development of hypertension and bradycardia (depending on the dose and rate of administration).
In combination with cardiac glycosides winstrol for sale may increase the risk of cardiac arrhythmias, additive inotropic effects (ECG monitoring is required).
Before the introduction of a patient in a state of shock hypovolemia should be corrected by introducing plasma and other blood liquids. The infusion should be under the control of diuresis, the minimum volume of blood (IOC), blood pressure (BP), ECG. The decrease in urine output without hypotension indicates the need for dose reduction. Patients treated during the last 2-3 weeks of medication from the group of MAO inhibitors, the initial dose of should not exceed 10% of the usual dose.
In pregnant women use the drug only if the expected benefit to the mother outweighs the potential risk to the fetus (in the experiment revealed adverse effects on the fetus). unknown – whether into breast milk.
To reduce the risk of extravasation, if possible, should be administered in a large vein. To prevent tissue necrosis in case extravasal contact with the drug should immediately conduct infiltration of 10 to 15 mL of 0.9% sodium chloride solution isotonic with 5 to 10 mg of phentolamine.
In 5 ml concentrate for solution for infusion into transparent colorless glass vials, type 1, with the point of fracture blue. 5 vials are placed in sealed plastic trays. On 1 pallet together with instructions for use in a cardboard box. steriods for sale ganabol steroid buy horse steroids